Thanks @SRRP! I received some answers in the Google group. I took it right before bed with no problems. I had some slight headaches and joint pain, but I think that might have been related to being on vacation, and drinking and sleeping in a strange bed! I am also experiencing extreme vaginal dryness right now. I did not expect that, since I assume O should be right around the corner. My 5-day supply was less than $3 at my local pharmacy. I got a generic version.